Research Articles
Strategies for Improving Reproducibility in High-Throughput Experimentation: From Computational Methods to FAIR Data
This article provides a comprehensive guide for researchers and drug development professionals seeking to enhance the reproducibility of high-throughput experiments.
Combating Reagent Evaporation in Automated Synthesis: Strategies for Stable Assays and Reliable Drug Discovery
This article addresses the critical challenge of reagent evaporation in automated synthesis and high-throughput screening (HTS) platforms, a pervasive issue that compromises data integrity, reduces reproducibility, and increases costs in...
A Complete Guide to Minimizing Spatial Bias in Microtiter Plate Assays for Robust Drug Discovery
Spatial bias presents a significant challenge to the reliability and reproducibility of high-throughput screening (HTS) data in biomedical research and drug development.
Automating Biopharma: AI-Driven Strategies for Reaction Scale-Up and Purification
This article provides a comprehensive guide for researchers and drug development professionals on integrating automation and artificial intelligence into reaction scale-up and product purification.
Radial Synthesis Systems: Revolutionizing Automated Organic Molecule Library Production
This article explores the transformative role of radial synthesis systems in the automated construction of organic molecule libraries, a critical task for drug discovery and development.
Automated Fast-Flow Synthesis of Peptide-PNA Conjugates: A Transformative Platform for Accelerated Therapeutic Development
The therapeutic potential of peptide nucleic acids (PNAs) is often limited by challenging synthesis and poor cellular delivery.
Closed-Loop Optimization of Suzuki-Miyaura Coupling: Accelerating Reaction Discovery for Pharmaceutical Development
This article provides a comprehensive guide for researchers and drug development professionals on implementing closed-loop optimization for Suzuki-Miyaura cross-coupling reactions.
Automated Reaction Monitoring: Integrating UPLC-MS and NMR for Smarter Chemical Synthesis
This article explores the transformative integration of UPLC-MS and NMR spectroscopy for automated reaction monitoring, a cornerstone of modern high-throughput research in drug development and chemical synthesis.
Implementing AI-Driven Computer-Aided Synthesis Planning (CASP): A Strategic Guide for Accelerating Drug Discovery
This article provides a comprehensive guide for researchers and drug development professionals on implementing Computer-Aided Synthesis Planning (CASP).
Liquid Handling Robots for Chemical Reaction Setup: A 2025 Guide to Precision, Efficiency, and Automation
This article provides researchers, scientists, and drug development professionals with a comprehensive analysis of liquid handling robots for chemical reaction setup.