Research Articles
Systematic Strategies for Troubleshooting Failed Organic Reactions: From Foundational Principles to AI-Driven Solutions
This article provides a comprehensive guide for researchers and drug development professionals facing challenges with failed organic reactions.
Optimizing Organic Reaction Yields with Machine Learning: From Data to Discovery
This article explores the transformative impact of machine learning (ML) on optimizing yields in organic synthesis for researchers, scientists, and drug development professionals.
From Milligram to Kilogram: A Modern Guide to Scaling Up Optimized Organic Reactions
Scaling up optimized laboratory reactions to industrial production is a critical, high-risk step in drug development and fine chemical manufacturing.
Flow Chemistry vs Batch Organic Synthesis: A Modern Guide for Researchers and Drug Development
This article provides a comprehensive comparison of flow chemistry and batch synthesis for researchers and professionals in drug development.
Modern Catalyst Screening Methods for Organic Reactions: From AI-Driven Discovery to Biomedical Applications
This article provides a comprehensive overview of contemporary catalyst screening methodologies that are accelerating discovery in organic synthesis and drug development.
Parallel Synthesis in Organic Chemistry: Accelerating Drug Discovery through High-Throughput Methodologies
This article provides a comprehensive overview of parallel synthesis techniques and their transformative impact on organic chemistry, particularly in drug discovery.
Modern Design of Experiments for Organic Synthesis: Integrating AI, Automation, and Green Chemistry
This article provides a comprehensive overview of modern Design of Experiments (DOE) methodologies for optimizing organic synthesis.
HTE Batch Modules for Reaction Screening: A Complete Guide for Accelerated Drug Discovery
This article provides a comprehensive overview of High-Throughput Experimentation (HTE) batch modules for chemical reaction screening, tailored for researchers, scientists, and drug development professionals.
Closed-Loop Optimization of Organic Reactions: A Machine Learning-Driven Paradigm for Accelerated Drug Discovery
This article explores the transformative impact of closed-loop optimization, which integrates high-throughput experimentation (HTE) with machine learning (ML), on accelerating the development of organic syntheses.
Automated Synthesis Platforms in Organic Chemistry: A New Paradigm for Drug Discovery and Research
Automated synthesis platforms are revolutionizing organic chemistry by integrating robotics, artificial intelligence, and advanced engineering to accelerate molecular discovery.